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July 22/29, 1998

Gastrointestinal Symptoms Following Olestra Consumption

Author Affiliations

Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor

JAMA. 1998;280(4):325-327. doi:10-1001/pubs.JAMA-ISSN-0098-7484-280-4-jbk0722

To the Editor.—Procter & Gamble's movie theater study1 does a good job of answering the wrong questions. It fails to demonstrate a significantly increased incidence of gastrointestinal (GI) effects from a one-time, variable olestra exposure. But it sheds little light on what will happen when large numbers of Americans consume olestra over prolonged periods. Also, JAMA's "Editor's Note" was incorrect in stating that "controlled studies [on olestra's GI effects] have not been reported."2