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Article
July 13, 1935

THE ACTION OF MERCUROCHROME AND OTHER DRUGS: ON NORMAL HUMAN SKIN AND IN INFECTED WOUNDS

JAMA. 1935;105(2):100-104. doi:10.1001/jama.1935.02760280012004
Abstract

To be worthy of clinical use, any antiseptic must be able to survive severe criticism and to find its true level on a factual basis, confirmed by the studies of at least two independent groups of observers. Quite aside from fallacies arising from assumptions based on analogy, and from the personal equation, the problem of evaluating any antiseptic, especially one used in several fields, is extremely complex, because of the many factors involved. Unintentional errors of technic and of reasoning are to be found in most articles dealing with this highly specialized field within a field, in which the pitfalls are not always obvious, even to the experienced worker. However, probably the chief merit of such a controversy is the instigation of further research. This may be of value not only for the drug or drugs in question but also in relation to the whole problem of antisepsis, by the

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