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June 26, 1943


Author Affiliations

APO 827, c/o Postmaster, New Orleans.

JAMA. 1943;122(9):636. doi:10.1001/jama.1943.02840260064024

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To the Editor:—  Referring to the use of the term "the ring test of Lepehne" in the paper "The Functional Value of the Liver in Heart Disease" by Chávez, Sepúlveda and Ortega I. (The Journal, April 17), Lepehne, now working at Boston University School of Medicine, is not responsible for the application of the ring technic now used so extensively in the performance of the van den Bergh reaction ("direct" reaction). In an editorial in the Journal of Laboratory and Clinical Medicine a decade ago Magath did give Lepehne credit for the test, remarking that it was "rediscovered by Elton ten years later," but examination of Lepehne's report showed that while he tried overlaying the diazo reagent on serum rather than mixing it before I did, he did not appreciate its clinical value and stated that it afforded no advantage over the original technic. I believe I was the first

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