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The first portion of this book, by Loeper, deals with general therapeutics, including a study of nerve sedatives, hypnotics, analgesics, anesthetics and tonics. He considers bromides, valerian and borax sedatives to the general nervous system, and the drugs of the atropine series mesencephalon sedatives because of their value in parkinsonian tremor, which is not affected by the first mentioned group. The term "sympathicolytic" is proposed for sedatives of the sympathetic nerve system, and under this heading are classified ergotamine, yohimbine and crataegus. The belladonna series is spoken of as "parasympathicolytic" (why not "vagolytic") in contrast to the sympathicotonic epinephrine and ephedrine and the vagotonic physostigmine. Among the general anesthetics, evipal is given a rather special discussion, which it probably deserves. Under hypnotics, the synergism of trional and paraldehyde, and of opiates with chloral is emphasized; so is the increase in analgesic value of the combination of coal tar analgesics with
Thérapeutique médicale. VIII: Système nerveux. JAMA. 1935;105(7):536–537. doi:10.1001/jama.1935.02760330062030
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