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August 31, 1935


JAMA. 1935;105(9):667-676. doi:10.1001/jama.1935.92760350007009a

Note.  This article concludes a series of thirty-two articles on glandular physiology and therapy by various authors, published under the auspices of the Council on Pharmacy and Chemistry. The series of articles will be published in book form.—Ed.Perhaps no group of pharmaceutical preparations in recent years has been the subject of such extravagant claims as that comprising allegedly active materials derived from various glands, nonglandular organs and body fluids. Hardly a tissue or fluid of the body has escaped desiccation or extraction; substances so obtained are marketed in pills, tablets, capsules, vials and ampules for introduction into the body by every conceivable route. Only a small percentage of the many preparations are known to contain active material; and with the few exceptions (thyroid, liver, stomach, adrenal cortex, and some estrogenic principles) discussed later, the products administered by mouth have little effect even if they do contain some active