In the twelve years since the publication of a case report by Giordano and Bumpus1 progressively increasing interest has been shown in secondary tumors of the ureters. The rarity of true metastasis to the ureter from adjacent pelvic organs, so often the seat of malignant disease, is difficult to explain when one remembers the frequency of occurrence of carcinoma of the bladder and the fact that the lymphatic vessels of the two organs communicate, unless one agrees with Robinson2 that the lymphatic drainage of the lower portion of the ureters is downward. This is also true of other pelvic organs in both the male and the female. Even as rare a condition as primary carcinoma of the ureter appears to be, I am inclined to believe with Glas3 that true metastases are even rarer, and it appears that the histologic structure of the ureter is somewhat immune
WOODRUFF SR. SECONDARY TUMORS OF THE URETERA CONSIDERATION OF THE VARIOUS TYPES, WITH A REPORT OF TWO CASES. JAMA. 1935;105(12):925–931. doi:10.1001/jama.1935.02760380001001
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