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To the Editor:—
In the article by Dr. Herman O. Mosenthal on "Hyperglycemia: Evaluation in the Treatment of Diabetes," in The Journal, August 17, the statement is made by him and most of those who discussed the paper that diabetes is a contributing factor in the causation of arteriosclerosis. I believe Dr. Joslin is the most important sponsor for this view. It is rather curious that in the study of arteriosclerosis most observers have overlooked a rather simple observation, which completely disproves any metabolic origin in the causation of arteriosclerosis; namely, the complete independence in the incidence of arteriosclerosis between the general and pulmonary circuits (Moschcowitz, Eli: The Cause of Arteriosclerosis, Am. J. M. Sc. 178:244 [Aug.] 1929). A false perspective is given to the study of human arteriosclerosis when observations are confined, as is conventionally done, to the aorta and its branches. If, however, observations on the aorta
Moschcowitz E. HYPERGLYCEMIA. JAMA. 1935;105(13):1057. doi:10.1001/jama.1935.02760390051025
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