[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
October 12, 1935


JAMA. 1935;105(15):1187-1188. doi:10.1001/jama.1935.92760410001011

This case of chronic hereditary hemolytic jaundice is reported because the disease is relatively infrequent, because it presents many typical features, and because the hereditary aspect is represented by four generations.

H. M., a woman, aged 23, admitted to St. Francis Hospital, Dec. 1, 1934, complained chiefly of weakness, fulness of the left side of the abdomen, recurrent attacks of jaundice associated with abdominal pain, fever, nausea and vomiting. The first attack of jaundice occurred at the age of 10 weeks. Frequent menstruation had been present for about six months; it occurred every nine days and was of four or five days' duration. Ulcerations of the malleolar regions of both feet had been present as long as could be remembered.

The patient had had the acute exanthems of childhood and an appendectomy in October 1934.

The family history showed the interesting hereditary nature of this disease. The mother was living at the