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October 12, 1935


JAMA. 1935;105(15):1193. doi:10.1001/jama.1935.02760410037015

The ninetieth birthday of Sir Thomas Barlow serves as the occasion for a special issue of the Archives of Disease in Childhood—an official publication of the British Medical Association — devoted to infantile scurvy.1 The historical aspects of the occasion are especially illuminated by the reproduction of Barlow's original communication of 1883. The history has been sketched by Still and supplemented by an article on Cheadle by Poynton. Obviously, speculations prior to Barlow's paper approached the correct interpretation of this condition, but these contributions lacked that definite foundation in clinical and pathologic observation established for the first time by him. Barlow was the first, with the possible exception of Ingerslev— twelve years earlier—who clearly distinguished between rickets and infantile scurvy. His summation can scarcely be improved today. "The characteristic symptoms of the so-called acute rickets, viz., the special limb affection and the cachexia, with or without sponginess of