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October 26, 1935

Current Comment

JAMA. 1935;105(17):1354-1355. doi:10.1001/jama.1935.02760430044017

ADDICTION TO ENDOCRINE GLAND PRODUCTS  After careful consideration of the available terms, Patterson1 feels that, with the possible exception of the French word "manie," addiction most nearly expresses some unusual manifestations that may result from the continued use of certain endocrine gland extracts. Though most of the cases of the misuse of endocrine gland extracts quoted by him are properly an "abuse," some are comparable in their psychologic content with instances of overmastery by morphine, diacetylmorphine and alcohol, for which the term "addiction" is used. In the use of thyroid gland products, which he considers first, instances of ill effects from prolonged or poorly supervised administration are numerous. The development of symptoms of hyperthyroidism is the most common of these complications. The especial danger of this is in prolonged self administration, usually aimed at the treatment of obesity. There are, however, cases in which the psychologic factor is the

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