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November 30, 1935

Current Comment

JAMA. 1935;105(22):1776. doi:10.1001/jama.1935.02760480046014

NONSPECIFIC PROTEIN TREATMENT  In this issue appears the first of two special articles on nonspecific protein treatment, prepared under the auspices of the Council on Pharmacy and Chemistry. Hektoen1 discusses briefly the nature of the reactions to nonspecific proteins in the treatment of infectious diseases. Next week Cecil2 will review experiences and results with this treatment; he shows that modern protein treatment appears to have achieved "a permanent place for itself in modern therapeutics" not only of certain acute and subacute infectious diseases but also in other conditions, notably thrombo-angiitis obliterans. To this extent nonspecific protein treatment is a noteworthy achievement in empirical therapeutics of direct interest to the medical practitioner. Both articles point out that the effects of nonspecific proteins in infectious conditions are associated with nonspecific as well as specific anti-infectious processes. Differences in these effects in the same infection and in different infections cannot now