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December 14, 1935

Onchocerciasis with Special Reference to the Central American Form of the Disease

JAMA. 1935;105(24):2010-2011. doi:10.1001/jama.1935.02760500062028

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This is a monograph on the Central American form of onchocerciasis, a helminth infection of man, producing swellings around the adult worm, mainly on the head. It is associated with ocular complications resulting in blindness in extreme cases. Dr. Strong, who investigated the disease in Guatemala in 1931 and 1932, contributes the larger section, containing the epidemiologic and endemiologic studies, clinical and pathologic observations, ocular complications, transmission, immunity, microfilaricidal substances, public health aspects, prophylaxis and treatment. Dr. Sandground attacks the knotty problems of the classification of Onchocerca and critically analyzes the inadequate literature regarding this human helminth and related worms from the horse, cattle and antelope. He gives complete accounts of the adult male and female Onchocerca caecutiens from Guatemalan cases. Dr. Bequaert describes the insect vectors of the larval stages or microfilariae, namely, the black flies or Simuliidae, of the area of the disease in Guatemala, with studies of

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