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February 8, 1936


JAMA. 1936;106(6):469. doi:10.1001/jama.1936.02770060043014

The possibility of an etiologic relationship between chronic bone disease and the formation of urinary calculi was first suggested more than a hundred years ago.1 At that time it was noted that the injury of vertebrae may be followed by the formation of renal calculi. Since then a number of cases have been recorded in which formation of urinary calculi has occurred subsequent to injuries or to diseases of various bones. The period following the World War developed reports of this type presumably because of the increased incidence of bone injury and disease from gunshot wounds and amputations. Recently2 the literature on the subject has been reviewed and fourteen additional cases have been described. Urinary calculi were found in patients with such varied bone diseases or conditions as osteomyelitis, fractures of long bones, fractures of the pelvis, amputations of the extremities, tuberculosis of the hip joints, arthritis deformans

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