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March 21, 1936

Handbuch der experimentellen Pharmakologie

JAMA. 1936;106(12):1034. doi:10.1001/jama.1936.02770120066034

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This volume of the Handbook on Experimental Pharmacology is devoted most especially to an exhaustive exposition of the pharmacology of bismuth (over 500 pages), a discussion of what is known about molybdenum and tungsten, and a chapter on the rarer earth metals. In pharmacologic action the latter resemble one another and aluminum as well and, to a certain extent, thorium. Especially marked is the resemblance between neodymium and praseodymium; while there are, on the other hand, rather marked differences in case of ytrium, lanthanum and scandium. It has been shown that cerium cannot replace calcium or magnesium. The use of cerium oxalate as an antiemetic seems to have a certain amount of experimental justification. Colloidal molybdenum seems to have chemotherapeutic possibilities in various infections, including tuberculosis. In the section on bismuth, August W. Forst discusses interestingly the history of the therapeutic use of bismuth compounds and points out that "magisterium

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