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March 28, 1936


JAMA. 1936;106(13):1063-1070. doi:10.1001/jama.1936.02770130013005

It is surprisingly strange how slowly the medical profession is coming to appreciate the importance of cortical kidney infection due to the various types of cocci, as well as the various clinical pictures of this condition and its very definite relation to perinephritis, to perinephric abscess and probably to chronic sclerosing perinephritis. In this paper I shall analyze some of my observations, which I have attempted to describe in part previously and which corroborate much that is scattered here and there in the literature.

Though the clinical picture presented by these cortical coccic infections in previously normal kidneys may vary from the most acute disease to a more or less chronic one, usually the diagnosis can be made and proper therapy instituted before irreparable harm to the kidney or to the patient is done. There is a distinct and definite difference between these cases and the bacillary infections: colon, proteus,