Many of the symptoms of adrenal insufficiency are those commonly associated with dehydration and depletion of the bases of the animal body, chiefly sodium. In cases of Addison's disease the administration of an adequate amount of sodium tends to produce a more nearly normal state of hydration and corrects the sodium deficit. Harrop1 first suggested that sodium chloride restriction precipitated crises in patients suffering from Addison's disease and could be used in this manner to establish a diagnosis in questionable cases. The following case is presented as evidence that such a test is not reliable in all instances :
REPORT OF CASE
—Mrs.E. W., aged 39, admitted to the medical service of Dr. H. A. Reimann at the University Hospitals in July 1934, gave the following history : She had not been strong since she suffered from "milk leg" following the birth of her last living child
Johnson RM. FAILURE OF SODIUM CHLORIDE RESTRICTION TO PRECIPITATE CRISIS IN A CASE OF ADDISON'S DISEASE. JAMA. 1936;107(4):278–279. doi:10.1001/jama.1936.92770300001009
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