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September 26, 1936


JAMA. 1936;107(13):1041-1043. doi:10.1001/jama.1936.92770390002010a

True myelogenous leukemia with cutaneous involvement is a relatively rare clinical entity, only sixteen cases having been reported. The early literature has been reviewed by Barney1 and Hollander, Kastlin, Permar and Schmitt,2 who added two additional cases. Since the publication of these reports, one case has been described by Patrassi.3

The case here reported was diagnosed as cutaneous myelosis and the clinical observations were substantiated by subsequent biopsy and autopsy studies.

REPORT OF CASE  R. C., a white man, aged 41, on admission to the Simpson Memorial Institute, Aug. 11, 1933, complained of pain in the left upper quadrant. Since January 1933 he had noted increasing weakness, palpitation and dyspnea on exertion. More recently a constant pain was present in the left upper quadrant. One month previous to admission the patient accidentally noted a mass in this region. He had had hemorrhoids for two years but noticed