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This case is of interest only because of the extremely rapid growth of a large breast tumor in a girl, aged 14 years. While the Cohnhein theory of the origin of such tumors arising from misplaced islands of tissue is in many instances doubted, it is difficult to explain this case on any of the other theories.
This girl had normal appearing, symmetrical breasts with no evidence of nodule formation in February 1935. Sometime during April she began experiencing a "heaviness" of the right breast and noted that the nipple areola on this side appeared wider. Sometime in May she noticed that the entire right breast was larger than the left, and the "feeling of heaviness" was increased. For relief her mother made her a "carrier" to help support this breast. From this time on the breast grew very rapidly. Within two months from the time the patient first complained
Markowitz B, Howell HL. RAPID GROWTH OF A LARGE BREAST FIBROMA IN A YOUNG GIRL. JAMA. 1936;107(13):1043–1044. doi:10.1001/jama.1936.92770390004010b
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