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November 13, 1937


JAMA. 1937;109(20):1626. doi:10.1001/jama.1937.92780460001010

While ganglions may disappear spontaneously, years sometimes elapse before this takes place. One patient, a physician, had a ganglion for ten years before spontaneous rupture occurred. Since ganglions usually occur on the wrist and are embarrassing deformities, and since they may also cause discomfort, most patients prefer prompt treatment.

Of the many methods that have been advanced in the past for the treatment of ganglions, the one that has been generally accepted is excision.1 It is obvious that the simpler methods that have been recommended—that is, forcible rupture with a heavy object such as a book, puncture with a hypodermic needle, injection of an irritant such as iodine, scarification of the walls of the sac, and the like—are not always successful; otherwise operation would not be advocated.

The pathogenesis of ganglions is not too well understood; the commonly accepted theories are that they may be due to a herniation

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