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October 21, 1939

Dissociation of Tubercle Bacilli: Investigations on the Mammalian Types Including BCG

Author Affiliations

By J. Frimodt-Möller. Acta tuberculosea Scandinavica, Supplementum II. Paper. Pp. 256, with 49 illustrations. Copenhagen: Einar Munksgaard, 1939.

JAMA. 1939;113(17):1589-1590. doi:10.1001/jama.1939.02800420063024

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This extensive monograph in English on the dissociation of tubercle bacilli, presented to the University of Copenhagen in fulfilment of the requirements for the degree of doctor of medicine, also appears in the Acta tuberculosea Scandinavica. It is a laudable volume from the standpoint of reviewing ably a subject which has been controversial from its explosive inception about a decade ago. The author reports on part of extensive investigations (reported in 1932 and 1935) carried out in the tuberculosis department of the State Serum Institute at Copenhagen on matters relating to the types of tubercle bacilli. The purpose at hand was to study the variations of bovine and human strains isolated from tuberculous material from human beings and cultivated on artificial nutrient mediums and to examine any possible changes of their virulence. It was beyond the scope of the work to describe strains which displayed variations solely as a result

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