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October 21, 1939

Über die integrative Natur der normalen Harnbildung

Author Affiliations
 

Von Gösta Ekehorn, D: R med. Teile I, II und III. Paper. Pp. 616; 619-1137; 1139-1431. Helsingfors: Mercators Tryckeri, 1938.

JAMA. 1939;113(17):1592. doi:10.1001/jama.1939.02800420066033

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Abstract

This wordy treatise is written by a native of Sweden in German and published in Finland; the first sentence of the preface states that it is a continuation of the author's previous book "Principles of Renal Function," which was published in English. The author first assumes that the glomerular filtrate is an ultrafiltrate of the blood and that the kidney tubules are impermeable to creatinine and only slightly permeable to urea. He calls them "schlackenstoff" to distinguish them from "schwellenstoffe," or threshold substances, including salts and water. Later, however, he spends much space disproving the impermeability of the tubule for creatinine. He states that the glomerular capillary blood pressure may be so high as to equal half the normal systolic arterial pressure, and therefore the glomerular filtrate volume averages about one fourth the renal blood volume. On the assumption of impermeability to creatinine, he quotes tables from Rehberg's 1926 publication

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