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October 28, 1939


JAMA. 1939;113(18):1634-1637. doi:10.1001/jama.1939.02800430026007

Solid ovarian tumors, especially those producing endocrine changes, have been the subject of much discussion and investigation both by the pathologist and by the gynecologist during the past few years. Robert Meyer's1 work, reported in 1931, was probably the spark that first aroused interest in America. In this publication he described the dysgerminoma ovarii, the granulosa cell tumor and the arrhenoblastoma. Later numerous reports of these tumor types appeared in the literature at frequent intervals, as did also reports of Brenner cell tumors; Bland and Goldstein2 reviewed the literature and collected sixty cases of the latter type of tumor in 1935. Loeffler and Priesel3 in 1932 recorded six cases of ovarian tumors, which they termed "fibroma theca cellulari xanthomatodes ovarii," and in 1934 the same authors4 reported four additional cases of this type. In the same year Melnick and Kanter5 reported two similar cases, the