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Alsted thinks the evidence is sufficient to warrant the conclusion that duodenal ulcer in contrast to gastric ulcer was rare up to the early part of the present century. On the basis of a review of early and more recent Danish and foreign clinical material he believes that a reversal in the sex incidence of peptic ulcer has taken place. In earlier times the proportion of men to women was 1: 5 or 1:6, at the beginning of the present century it was 1: 1 and since 1920 it has been 3: 1. Duodenal ulcer in his opinion is rapidly increasing in both sexes, especially in men, whereas acute gastric ulcers are rapidly decreasing, especially in women (page 112). Then, in apparent contradiction to this observation, he says (page 135) "Nowadays no more men get ulcers than previously, but there are more who have them." In other words, there are
Studies on the Changing Incidence of Peptic Ulcer of the Stomach and Duodenum. JAMA. 1939;113(20):1834. doi:10.1001/jama.1939.02800450056030
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