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December 16, 1939


JAMA. 1939;113(25):2227-2229. doi:10.1001/jama.1939.02800500033008

Blood transfusion in recent years has become an increasingly important and simplified procedure in most well organized hospitals. The establishment of blood banks and the storing of blood have facilitated the use of this valuable therapeutic agent. The usual technic employed in the United States is that of the Cook County Hospital,1 consisting of the addition of 0.35 Gm. of chemically pure sodium citrate in physiologic solution of sodium chloride to each hundred cubic centimeters of blood. This gives an adequate amount of sodium citrate for the prevention of coagulation, and after sterility and typing tests and serologic tests for syphilis the blood is available for transfusion forabout ten days or more. Standardized serologic tests for typing and for the detection of syphilis give satisfactory results when carefully done. However, sterility tests on stored blood not only are technically hazardous to carry out but also give results difficult to