[Skip to Content]
[Skip to Content Landing]
Other Articles
December 16, 1939


JAMA. 1939;113(25):2231-2232. doi:10.1001/jama.1939.72800500003009b

Recently Rhoads and Panzer1 have stated that "bank blood" is an unsatisfactory source of plasma prothrombin for the treatment of patients with the hemorrhagic tendency associated with jaundice. Their results were based on the determination of the plasma prothrombin content of bank blood by the method of Quick.2

Quick's method for the determination of plasma prothrombin controls two of the four important factors which enter into the formation of a clot. An excess of calcium and thromboplastin are added to oxalated plasma in suitable amounts, and the time taken for a clot to form is considered the prothrombin time. In the Quick test no attempt is made to control the fibrinogen in the plasma.. Linton3 and Moss4 have demonstrated that the fibrinogen in the plasma of man and dogs is normal in the hemorrhagic tendency associated with obstructive jaundice. On the basis of their data, Quick