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December 30, 1939


JAMA. 1939;113(27):2387-2391. doi:10.1001/jama.1939.02800520013003

The concept of disease caused by increased function of parathyroid tissue has been firmly established since Mandl's1 successful removal of a parathyroid adenoma for osteitis fibrosa cystica in 1925. During the past thirteen years, more than 150 well studied cases of hyperparathyroidism have been reported and much has been added to our knowledge of the disease. However, a review of the literature revealed only one report dealing with pregnancy in a patient with hyperparathyroidism.2 It is our purpose in this communication to record such a case and to discuss the interesting problem that it presents.


History.—  A woman aged 29, an American-born dancer, was admitted to Mount Sinai Hospital with chronic hyperparathyroidism on Sept. 19, 1938, in the fourth month of her first pregnancy. Her family history was negative. She was a seven months infant weighing 5 pounds (2,268 Gm.) at birth. Her early history