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February 17, 1940

Semeiologia del midollo osseo: Studio di morfologia clinica

JAMA. 1940;114(7):606. doi:10.1001/jama.1940.02810070072030

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In the past six years many monographs dealing with sternal puncture have been published, but in no case has the reproduction of marrow cells equaled the excellent illustrations of Fieschi's book. This point is justly emphasized in the preface by Aldolfo Ferrata, the maestro of Italian hematology. The sixteen chapters cover a study of bone marrows from every type of blood dyscrasia and even include a discussion of the morphology of metastatic tumor cells. The author has attempted to carry the study of myelograms beyond the realm of percentages obtained by making differential counts and has emphasized the functional state of the marrow. He points out that there are three forces which regulate the composition of the marrow: a proliferative force, an evolutive or maturative force, and a migratory force which regulates the passage of cells into the blood stream. In order to study the proliferative force the author has

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