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February 17, 1940

Experimental Pharmacology and Materia Medica

JAMA. 1940;114(7):606. doi:10.1001/jama.1940.02810070072031

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This well known and much quoted work is a source book for experimentalists. The present edition, twice as voluminous as the first, is comprehensive in experimental methods, technic and subject matter. Directions are given in detail but they are not prolix. Detail makes the difference between success and failure in an experiment. Michelangelo said "Trifles make perfection, but perfection is no trifle." Jackson has followed the gleam of Michelangelo and has shown an enormous capacity for taking pains.

The unit of procedure is the experiment. The aim is to develop a knowledge and appreciation of general pharmacologic reactions. Since there are about 400,000 known organic preparations and about as many inorganic preparations, he has used the economic principle of grouping drugs according to systemic effects. The groupings include drugs acting on the (1) central nervous system, (2) heart and circulation, (3) respiration, (4) alimentary tract, (5) kidneys and (6) involuntary nervous

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