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This monograph by Selander concerns the clinical and statistical study of epidemic and sporadic icterus. In reviewing the literature the author notes that the infective agent of icterus is unknown and that there are differences of opinion as to whether there are two distinct types of the disease or whether there is only one manifesting itself sporadically or in epidemics. In an attempt to clarify the issue the author studied 1,200 cases and reports as follows:
As far as onset is concerned, no difference between the two forms could be determined, although sporadic icterus occurred often in the age bracket between 2 and 7 years, while the epidemic form was more frequently seen in the 7 to 15 year group. Sex seems to have no influence on the incidence of either type of icterus.
In an epidemic in Gotland the reported incidence among younger patients was greater in
Epidemischer und sporadischer lkterus: Eine statistisch-epidemiologische und klinische Untersuchung. JAMA. 1940;114(7):607. doi:10.1001/jama.1940.02810070073033
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