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March 9, 1940


JAMA. 1940;114(10):846-847. doi:10.1001/jama.1940.02810100012004

Schizophrenia is a major medical and economic problem. Twenty-one years ago Pollock said:  If some unknown disease should strike down and kill 1,000 young people in New York City during the current year, do you think the medical profession, the newspapers, and the public generally would view the matter with complacency? Yet dementia praecox will come into this city as a masked enemy and steal away the minds of 1,000 young men and women and condemn them to a living death this year... and scarcely no public mention of the matter will be made.A true rebirth phenomenon has insidiously manifested itself during the past half decade. It has been given impetus by the report of Meduna on the convulsive treatment of schizophrenia through the use of pentamethylenetetrazol (metrazol, cardiazol). The results achieved by Sakel using insulin as a method of inducing pharmacologic shock received wide publicity.The great attention

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