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Early in 1937 I became conscious of the fact that I had almost lost my taste for food. The condition seemed to date from about the first of the year; I had been enjoying the flesh-pots over the holidays, and I assumed it was the result of that. But it continued and finally I concluded it was a permanent deterioration in my taste, for which, however, I had nothing to account. It was not a true loss of appetite because I would get hungry, but a loss of taste for food. It was so marked that I found it difficult to eat. In four months, by May, I had lost 20 pounds, from 185 to 165. A sudden unaccountable loss of 20 pounds in weight in an old man is a matter for concern, and I sought expert advice. I was thoroughly studied and nothing of importance was found, and
William Allen Pusey. AN UNFAMILIAR CAUSE OF LOSS OF WEIGHT. JAMA. 1940;114(16):1548. doi:10.1001/jama.1940.62810160005010d