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April 20, 1940


JAMA. 1940;114(16):1576. doi:10.1001/jama.1940.02810160078031

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To the Editor:—  In a recent letter from Buenos Aires (The Journal, March 2, p. 816) your correspondent stated that Agote, in November 1914, was the first to use sodium citrate in the transfusion of human blood. This statement requires correction. Seven months before Agote, Hustin (Note sur une nouvelle méthode de transfusion, Soc. roy. d. sc. méd. de Bruxelles72:104 [April 6] 1914) used citrated blood, though in a strongly diluted form. As Hédon (Note complémentaire sur la transfusion du sang citrate, Presse méd.26:57 [Jan. 31] 1918) pointed out, Hustin's method was really an infusion of strongly diluted blood mixed with sodium citrate and dextrose.It was a curious coincidence that both Agote's (Nuevo procedimento para la transfusión del sangre, An. Inst. modelo de clin. méd., January 1915), and my (A New and Greatly Simplified Method of Blood Transfusion, M. Rec.87:141 [Jan. 23] 1915)

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