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April 27, 1940


JAMA. 1940;114(17):1611-1616. doi:10.1001/jama.1940.02810170007002

This study, consisting of an analysis of 212 histologically proved cases of Hodgkin's disease, is made in the hope of contributing further data to this important subject.

Of these cases, 126 were followed by the Radiation Therapy Department of Bellevue Hospital and eighty-six at the New York City Cancer Institute during the eleven years 1926-1936 inclusive. Fifty-four additional cases clinically diagnosed as Hodgkin's disease were omitted because histologic examination was not made. Of the cases studied, 123 remained under observation until death occurred. Autopsy was performed on thirty-four, or 28 per cent.

AGE AND SEX INCIDENCE  That Hodgkin's disease may occur at any age is demonstrated in this series, in which the youngest patient was 6 and the oldest 76. A study of the age distribution reveals the greatest number of cases occurring in the third decade.The youngest patient recorded in the literature is that of Priesel and Winkelbauer,