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May 18, 1940


JAMA. 1940;114(20):2010-2015. doi:10.1001/jama.1940.62810200015009

THE THERAPY OF ACUTE PERIPHERAL CIRCULATION FAILURE: SYNCOPE, SHOCK AND COLLAPSE  In Collaboration with Dr. Lindon SeedAcute circulatory failure may be of three etiologic types: It may be due to heart failure (q. v.), to hemorrhage (q. v.) or to failure of the peripheral circulation. To distinguish between these types carefully is of practical therapeutic importance because digitalis bodies are likely to be of value in only certain of the cardiogenic types and may be harmful in others.In the type due to hemorrhage, the filling of the depleted vessels is of prime importance and, when this is due to loss of blood volume, prompt blood transfusion is the remedy. In this condition vasoconstrictor drugs may do harm.Failure of the peripheral circulation includes a number of clinical syndromes characterized by inadequacy of circulating blood volume (absolute or relative) due to causes other than hemorrhage. In traumatic shock there is