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May 18, 1940


JAMA. 1940;114(20):2021. doi:10.1001/jama.1940.02810200049012

Effective therapy in the control of oxyuriasis is not yet available, though many therapeutic measures have been proposed. The fact that pinworm infestation is usually a familial condition involving several or all members of a family does not make it any easier to control. A recent contribution by the United States Public Health Service1 presents the results of tests with santonin and hexylresorcinol. Santonin has been long recommended; hexylresorcinol was first used in 1932.2 The tests were made on sixty-two persons, outpatients of a clinic for parasitic diseases maintained in one of the hospitals of Washington, D. C., consisting predominantly of children (75 per cent) of the lower economic level. Diagnosis in all cases was made by means of a special cellophane swab.3 Inability to supervise posttreatment swab examinations closely did not permit making as many as seven such examinations in each case—the number which, according to