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November 30, 1963

Colonel Hoagland replies in the letter which follows

JAMA. 1963;186(9):874. doi:10.1001/jama.1963.03710090074025

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The low incidence of BFP reactions in mononucleosis was explained. The reason given by Dr. Kostant was given by me; additional explanations were inadequate criteria for diagnoses and excessive importance given to isolated case reports. My purpose was to debunk the cliché that BFP reactions occur frequently in mononucleosis. There was no intent to compare the frequency of false reactions in different serologic tests. My use of modern tests does not invalidate my conclusion: that it is time to expunge the fallacy of the frequently occurring BFP from the lore of mononucleosis.

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