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December 21, 1963

Peptic Ulcer and Pulmonary Disease in Coal Miners

JAMA. 1963;186(12):1061-1064. doi:10.1001/jama.1963.03710120043009

Opinions differ as to whether there is an interrelationship between peptic ulceration and pulmonary disease. In 168 miners occupationally exposed to soft-coal dust, a prevalence of peptic ulcer of 18.5% was found. Key features of the investigation were fluoroscopic and film evaluation of the upper gastrointestinal tract, roentgenogram of the chest, and studies of pulmonary function. No greater prevalence was noted among those with abnormal physical or functional pulmonary findings than among normal subjects. No relationship was indicated between a history of cigarette smoking or alcohol consumption and ulcer. It is probable that the "high" occurrence of ulcer was related to the fact that these men were actively examined for upper gastrointestinal disease, but some other factor, such as occupational stress, may have contributed to these findings.