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December 21, 1963

Heparin: Metabolism, Physiology and Clinical Application.

JAMA. 1963;186(12):1104. doi:10.1001/jama.1963.03710120086029

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The author attempts to compile the literature on heparin which has appeared in the past 20 years. The bibliography at the end of each chapter is generally extensive and up to date. The book, however, would have benefited by more careful editing of the contents. There are typographical errors, mistakes in grammar, and repetition of references in the same listings.

The book is divided into two parts: the chemistry, biochemistry and physiology of heparin and the clinical application of this drug. The chapters in the first part deal with such subjects as the chemistry and metabolism of heparin, the actions and functions of this drug, and its role as a lipid-clearing agent. Discussion of the clinical usage of heparin includes the effects of this agent on thrombo-embolic and atherosclerotic diseases and a number of other conditions.

The indices are adequate, the format pleasing. The volume may help research workers and

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