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February 1, 1964

Survival of Patients With Sickle Cell Anemia

JAMA. 1964;187(5):377. doi:10.1001/jama.1964.03060180063031

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To the Editor:—  Recently, Gause et al (JAMA186:624 [Nov 16] 1963) correctly called attention to the fact that some patients with sickle cell disease (SS genotype) may survive for many years, and, in turn, presented a 52-year-old man as being possibly the oldest reported living patient with this abnormality. However, Sydenstricker et al (Amer Pract13:584 [Sept] 1962) described a 59-year-old man with sickle cell anemia and documented nine other examples of prolonged survival with this disorder. Our experience with sickle cell disease is similar to the observations of Sydenstricker and associates. The oldest person with this malady presently under our care is 50 years of age.

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