The complications associated with diabetes often constitute the major clinical and autopsy findings. A report by Norris and Yunis, in the February issue of the Archives of Pathology, suggests that there is a greater prevalence of submucosal degeneration of the seminal vesicles and vasa deferentia associated with aging in diabetics than in normal subjects. Submucosal degeneration is a granular, faintly basophilic change in the connective tissue underlying the epithelium, distinguishable from amyloid deposits. It appears to be particularly more frequent among diabetics of the 70-to-79-year age group (61%) than in control patients of the same age (14%). If the increased incidence of submucosal degeneration in aged diabetics is confirmed, the etiology will probably become a focus of controversy, as is that of amyloid, a substance which it resembles.
Diabetics are also subject to more extensive calcification within the wall of the vas deferens and the walls of the regional small
AGING IN THE DIABETIC. JAMA. 1964;187(8):611. doi:10.1001/jama.1964.03060210061018
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