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June 29, 1964

Liver Disease of Long Duration

JAMA. 1964;188(13):1160. doi:10.1001/jama.1964.03060390062022

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To the Editor:—  The question asked in the Dec 21, 1963, issue of The Journal (186:1109) in regard to cirrhosis that might have been present for 20 years is reminiscent of a case Dr. P. E. Steiner and I reported in Cancer (7:475, 1954). The patient was a 69-year-old Negro woman with complaints of swelling of abdomen and legs. She admitted to drinking a moderate amount of beer. Her physician stated that she was treated for ascites from 1898 to 1902. Repeated paracenteses yielded as much as five gallons of ascitic fluid. She was treated with arsenic and mercury and, after disappearance of ascites, a large ventral hernia was repaired in 1903.She then became asymptomatic and remained so for over 31 years. At necropsy the nodular, fibrotic liver contained a large, soft, liver cell carcinoma. The inferior mesenteric vein was greatly dilated and opened into the inferior

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