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Medical News & Perspectives
August 24, 1964

Role of Vitamin B6 Is Analyzed In Central Nervous System Disorders

JAMA. 1964;189(8):27-28. doi:10.1001/jama.1964.03070080065037

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Abstract

A variety of central nervous system (CNS) disorders may result from abnormal metabolism of vitamin B6, David B. Coursin, MD, director of research at St. Joseph's Hospital, Lancaster, Pa, told an international symposium on the role of vitamin B6 [ill]n nutrition and metabolism in New York.

Coursin, in clinical studies, has raced certain types of convulsive seizures and mental retardation to defective metabolism of B6.

Coursin studied two groups of infants and children: (1) those with biochemical and clinical changes resulting from diets deficient in B6 and (2) those with clinical and metabolic [ill]bnormalities due to inborn errors of B6 dependency.

B6 varies in the degree to which it [ill]s involved in a variety of metabolic [ill]ystems, Coursin pointed out, and [ill]onsequently there is no single test hat is indicative of need.

"Measurements obtained from diagnostic procedures such as the electro[ill]ncephalogram, hemotological studies, ransaminases, tryptophan

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