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Clinical Notes
August 31, 1964

Hemophilus influenzae Pyarthrosis in an Adult

JAMA. 1964;189(9):694-695. doi:10.1001/jama.1964.03070090044016

Infection due to Hemophilus influenzae is generally considered to be a disease of infancy and early childhood, and its occurrence in an adult is rare. With advancing age, resistance to H influenzae increases, as shown by the bactericidal action of most adults' serum on the organism.1, 2 Meningitis due to H influenzae in adults is unusual; Merselis et al3 in a review of the medical literature in English collected 44 cases to which they added a series of 11.

A much rarer manifestation of disease due to the organism is pyarthrosis with only three cases previously described in adults. Dyer et al4 described a case which involved a 48-year-old female with multiple articular involvement in whom joint fluid culture was positive for H influenzae; blood cultures were negative. The case of a 59-year-old female with pyarthrosis due to H influenzae was reviewed by Weaver and Sherwood.5 Meligrano

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