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Original Contributions
September 21, 1964

Pulmonary Disease Associated With Rheumatoid Arthritis

JAMA. 1964;189(12):914-918. doi:10.1001/jama.1964.03070120036009
Abstract

Clinical records of patients with rheumatoid arthritis were reviewed for instances of pulmonary disease which might be ascribed to the pathological process associated with rheumatoid arthritis. Twenty-seven patients met criteria of the American Rheumatism Association for definite rheumatoid arthritis. Diffuse interstitial pneumonitis and subsequent fibrosis of the lungs did occur as a part of the rheumatoid process. Typical manifestations of rheumatoid arthritis usually present before pulmonary disease; sometimes they are simultaneous; rarely, pulmonary disease appears first. Initial discernible lesions occur most often in the base of the lungs and roentgenographically appear like pneumonitis. This study showed that pulmonary disease is a rare manifestation of rheumatoid arthritis.

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