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Medical News
December 21, 1964

Tolnaftate Used in Treatment of Dermatomycoses

JAMA. 1964;190(12):38. doi:10.1001/jama.1964.03070250086049

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A recent study showed that in more than 85% of patients with superficial dermatomycoses, tolnaftate 1% solution, cream, or powder, used separately or together, produced clearing of lesions or marked reduction in target symptoms within eight weeks. In all cases, itching disappeared within a few days, a Washington, DC, physician reported at the annual meeting of the Southern Medical Association in Memphis.

The study also showed that tolnaftate—a potent, safe antifungal agent with an extremely low index of sensitization— was indicated in the topical treatment of tinea pedis, tinea cruris, tinea corporis, and tinea manuum.

In addition, the topical fungicide was effective against tinea versicolor due to Trichophyton rubum, T mentagrophytes, Malassezia furfur, and Epidermophyton floccosum, Arnold H. Gould, MD, associate clinical professor of medicine, dermatology, Georgetown University School of Medicine, said.

In other studies, tolnaftate has been shown to be effective against Microsporum audouini, but not effective against Candida

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