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February 23, 1963


JAMA. 1963;183(8):712. doi:10.1001/jama.1963.03700080120029

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Thalamotomy in Multiple Sclerosis.  —B. Broager and T. Fog (Acta Neurol Scand38:153 [Suppl 3] 1962) performed ventrolateral thalamotomy on four patients (aged from 30 to 40 yr) with severe multiple sclerosis, in an attempt to relieve incapacitating intention tremor. In all patients the disease was rapidly progressive, and was, relatively, of short duration. Intention tremor was improved in all patients as a result of thalamotomy. The authors believe, however, that the intervention is not indicated in patients with severe forms of multiple sclerosis because of the risk of exacerbation of other symptoms. The first patient died a few months after operation. Since his preoperative condition was extremely poor, it is unlikely that death was hastened by the intervention. In the second patient only, thalamotomy seems to have resulted, to some extent, in remission of disease symptoms. In view of the brief follow-up period, it is not possible to

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