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To the Editor:
—The injection of a substance into the amniotic cavity to terminate pregnancy is, of course, not new. In 1935, Boero (1936 Year Book of Obstetrics and Gynecology, p 53) advocated the injection of 40% formalin for interrupting pregnancy before fetal viability. In 1954, Stamm and De Watteville (1954-55 Year Book of Obstetrics and Gynecology, p 36) reported on the use of the Aburel method of interrupting gestation by withdrawing 100 cc of amniotic fluid and replacing it with an equal quantity of hypertonic saline solution. In 1958, Brosset (1959-60 Year Book of Obstetrics and Gynecology, p 61) recommended 50% glucose for induction of abortion and emptying of the uterus in cases of missed abortion. In 1960, Svane (1961-62 Year Book of Obstetrics and Gynecology, p 55) claimed good results from instilling saline extra-ovularly into the uterus by way of the cervical canal for interrupting pregnancy. In 1962,
J. P. Greenhill. Intra-Uterine Death. JAMA. 1963;183(8):715. doi:10.1001/jama.1963.03700080123037