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April 21, 1962

Influenza Myocarditis: Report of a Case with Observations on Serum Glutamic Oxaloacetic Transaminase

Author Affiliations

U.S.A.F., Columbus, Ohio

Senior Assistant Resident in Medicine, Department of Medicine, Ohio State University Health Center.

JAMA. 1962;180(3):204-208. doi:10.1001/jama.1962.03050160020005

This report is the study of a case of acute myocarditis with an associated elevation of influenza A complement fixation titer and complete absence of underlying heart disease. The patient had a 13-day elevation of serum glutamic oxaloacetic transaminase (SGO-T) which was felt to be related to the activity of the myocarditis. The literature concerning influenza myocarditis and SGO-T changes in myocarditis was reviewed. It was concluded that the patient's clinical course and SGO-T changes were compatible with those seen in myocarditis of varied etiology, and that a prolonged elevation of SGO-T may be of some assistance in making the difficult diagnosis of myocarditis. This is the first reported case in which underlying coronary artery disease was excluded by coronary angiography.