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In dissemination of medical knowledge it is often useful and interesting, rather than to discuss disease entities from an etiological or pathological point of view, to consider instead a single symptom or sign, or a group of symptoms and signs, along with the various problems they may provoke, much in the manner an individual physician might approach a new patient. This method of presentation is the one used by Alfred Huber, the Swiss ophthalmologist, in his scholarly new monograph entitled "Eye Symptoms in Brain Tumors." The author states, on the basis of his experience in examining and following 1,600 cases of brain tumor in the Clinic of Prof. H. Kravenbühl in Zurich, that in about 60% of the series, ocular abnormalities were among the initial clinical findings. He further feels that "the majority of eye signs in brain tumors actually are of diagnostic and even localizing significance." Emphasis is placed
Matson DD. Eye Symptoms in Brain Tumors. JAMA. 1962;180(4):349. doi:10.1001/jama.1962.03050170081026
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