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April 28, 1962

Pathologic Physiology; Mechanisms of Disease

JAMA. 1962;180(4):350. doi:10.1001/jama.1962.03050170082032

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Since the appearance of the second edition of this work (reviewed in The Journal May 26, 1956), there has been extensive revision, with special attention to genetics and chromosomes, water and electrolyte balance, protective mechanisms of the lungs, functions of the gallbladder and pancreas, and diseases of the nervous system.

The present edition is a heavy volume in the literal sense, but it is also heavy reading in the sense that the text often seems unnecessarily difficult. It is obviously intended for readers who already have a considerable grasp of anatomy, biochemistry, and normal physiology. It is not designed to be read continuously, page after page, but to be picked up for occasional reading or to be consulted for particular purposes. One must, therefore, regret the frequent occurrence of abbreviations that cannot be found either in the index or in current dictionaries. Mystifying new terms like "hemocholinium HC3" (p.

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